Chitin and Chitosan for Regenerative Medicine by Pradip Kumar Dutta

By Pradip Kumar Dutta

The booklet is a superb reference for scientists, researchers and scholars operating within the box of parts of biopolymeric biomaterials, biomedical engineering, therapeutics, tissue engineering and regenerative drugs. The booklet is split into components: half i'm going to concentrate on the tissue engineering and half II makes a speciality of therapeutics, functionalization and computer-aided innovations. The ebook includes thirteen chapters contributed by way of 20 overseas individuals who're prime specialists within the box of biopolymers and its purposes. it is going to concentrate on the developments of chitin and chitosan in regenerative medication.

Regenerative drugs in tissue engineering is the method of changing or regenerating human cells, tissues, or organs to revive or identify basic functionality. it truly is a really revolutionary box of drugs which can, within the close to destiny, aid with the dearth of life-saving organs to be had via donation for transplantation vis-a-vis regenerative drugs specializes in therapeutics, functionalization and computer-aided techniques.

It additionally covers actual and chemical facets of chitin and chitosan, structural differences for biomedical functions, chitosan dependent scaffolds and biomodelling in tissue engineering, nanomedicines and healing functions. With the wide variety of purposes, the area is watching for biopolymers to function the foundation for regenerative medication and biomedical applications.

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Chien Y, Liao YW, Liu DM, Lin HL, Chen SJ, Chen HL, Peng CH, Liang CM, Mou CY, Chiou SH (2012) Corneal repair by human corneal keratocyte-reprogrammed iPSCs and amphiphatic carboxymethyl-hexanoyl chitosan hydrogel. Alonso MJ, Sanchez A (2003) The potential of chitosan in ocular drug delivery. Hosny KM (2009) Preparation and evaluation of thermosensitive liposomal hydrogel for enhanced transcorneal permeation of ofloxacin. Bitar KN, Raghavan S (2012) Intestinal tissue engineering: current concepts and future vision of regenerative medicine in the gut.

Cheng et al. used an injectable thermosensitive chitosan/gelatin/ glycerol phosphate hydrogel for the controlled delivery of ferulic acid (FA). FA is an antioxidant and can relieve H2O2-induced oxidative stress on the NP cells. Controlled delivery of FA from the hydrogel decreased the oxidative stress on NP cells and showed a decrease in cellular apoptosis [158]. 9 Cardiac Regenerative Engineering Cardiac tissue regeneration pertains to repairing heart tissue and restoring the functioning ability of the heart [26].

4 Corneal Regenerative Engineering Cornea is a transparent layer of the eyeball that covers the iris and the pupil. It provides vision by refracting light to the retina and lens, functions as a physical barrier against microbes and dirt, and prevents damage to the eye by absorbing harmful UV light [125]. Availability of corneas from donors is limited, so research is currently underway to develop artificial substrates that have the properties required for transplanting corneal cells. Ozcelik et al.

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