By M. Rogers (Auth.)
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Extra info for Cells and Tissues. An Introduction to Histology and Cell Biology
What is cytoplasmic basophilia, and what does it signify? 1) The collagen is produced and secreted into the extracellular fluid in precursor form, to be polymerized there into the characteristic fibres described in Chapter 5. The macrophage The macrophage (Fig. 17) is the cell responsible for the removal of debris from the extracellular space of the body. It is usually more rounded than the fibroblast, and capable of active movement. The nucleus is typically slightly smaller than that of the fibroblast, but rounded; it has one nucleolus and, again, not a great deal of condensed chromatin.
The synthesis of non-protein material for export, particularly steroids, is carried on in smooth endoplasmic reticulum (SER), which is also associated with detoxification of drugs. The Golgi apparatus. The space inside the endoplasmic reticulum can be thought of as extracellular: once material is inside this space, it is out of the cytoplasm. But it seems 3. The anatomy of the cell 31 Fig. 10 TEM of cyto plasm from human hepatocyte, showing RER (centre) and SER (above). ) (Courtesy. Dr M. ) likely that the initial products of synthesis are diluted by a considerable volume of water, and concentration occurs before secretion.
Granular masses of haemosiderin may also occur in cells concerned in the breakdown of red blood cells: this is an iron-containing pigment derived from haemoglobin. Linking cell structure to function Our methods of observing cells inevitably influence our ideas about them, and nearly all the available techniques require the cells to be killed before we look at them. Cells are incredibly busy and active, with vesicles travelling in different directions, mitochondria writhing about more slowly, and everything shimmering with Brownian movement.