By Anthony Norman
Calcium-Binding Proteins in overall healthiness and sickness contains the papers ready by way of the invited audio system in addition to the various unfastened communications. The contributions are grouped in line with their common material, in accordance with the type made by means of the authors, e.g., Extracellular Metabolism: Calcium Homeostasis; Low-Affinity Calcium-Binding Proteins. There should be little question that calcium-binding proteins is a box of medical pastime to be able to proceed to provide result of nice curiosity to trendy biology.
This ebook is split into 8 sections, the 1st of which, take on extracellular calcium metabolism or calcium homeostasis. the following sections specialize in themes corresponding to low-affinity calcium-binding proteins; calcium and membranes, channels and delivery (pumps); the function of calcium in complicated metabolic techniques; and gene constitution of calcium-binding proteins and their expression. different chapters conceal actual reports on calcium-binding proteins, together with X-ray, crystallography, and NMR; structure-function relationships of calcium-binding proteins and their objectives; and calcium-binding proteins in wellbeing and fitness and illness.
This booklet could be of curiosity to practitioners within the fields of biology and medication.
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Extra info for Calcium-binding proteins in health and disease
C a B P w a s d e t e c t e d in t h e s u p e r n a t e by r a d i o i m m u n o a s s a y and a t a c o n c e n t r a t i o n of t h e o r d e r of 200-400 ng/mg protein. The i m m u n o b l o t from an S D S - P A G E s e p a r a t i o n of t h e p r o t e i n s r e v e a l e d t h e p r e s e n c e of an i m m u n o r e a c t i v e p r o t e i n w i t h a m o l e c u l a r w e i g h t of a b o u t 28,000 d a l t o n s , verifying t h e p r e s e n c e of bona fide c h i c k C a B P in this t i s s u e (not shown).
1982). Endocrine Rev. 3, 331. , Nguyen, A. , and Norman, A. W. (1987). J. Biol. Chem. 262, in press. , Friedlander, E. , Frandsen, B. , and Norman, A. W. (1979). Endocrinology 104, 1495. , and Noi^man, A. W. (1981). Endocrinology 108, 140. , Norman, A. , and Orci, L. (1982). Endocrinology 110, 2216. Norman, A. , Frankel, B. , Heldt, A. , and Grodsky, G. H. (1980). Science 209, 823. Cade, C, and Norman, A. W. (1986). Endocrinology 119, 84. , and Norman, A. W. (1985). Diabetes 34, 315. , and Norman, A.
F . , and Manuscript submitted. G. (1986). , E v a n s , R . E . G. (1986). In press, Cell. A. , and Dreyfuss, G. (1986). Science 2 3 1 , 1534. THE VITAMIN D ENDOCRINE SYSTEM: PLEIOTROPIC INTERACTIONS WHICH CONTRIBUTE TO CALCIUM HOMEOSTASIS L. Cancela, I. Nemere, G. Theofan, V. Leathers, H. Reichei, E. Belk, Y. Fujisawa, H. Ishida, J. E. Bishop, G. Jones, P. P. Minghetti and A. W. Norman Division of Biomedical Sciences & Department of Biochemistry University of California Riverside, California I.